On the role of intestinal microbiota in the development of food allergy from the positions of modern intestinal microbiology
The prevalence of atopic diseases, including atopic dermatitis, food allergy, allergic rhinitis and asthma, has increased over the past decades and at present they affect approximately 20% of the population. The review discusses the role of microbiota in the pathogenesis of food allergy. As has been demonstrated, risk factors of food allergy are hereditary atopy, parity, mixed or imbalanced breast feeding, etc. Any of these factors realise their potential of initiating atopy or non-atopy through change in intestinal microbiota. As is known, dysbiosis develops in infancy, preceding the onset of sensitisation. Intestinal flora plays an important role in the development of tolerance to food allergens. Taking into account an immense species diversity of intestinal flora, the problem under discussion needs further investigation.
Key words: microbiota, food allergy, intestinal microbiology, immune mechanisms.
For citation: Abdullaeva G.D., Aminova A.I., Prodeus A.P., Kildiyarova R.R., Korsunskiy A.A., Yudina Yu.V., Gumbatova Z.F., Eryushova T.Yu. On the role of intestinal microbiota in the development of food allergy from the positions of modern intestinal microbiology. Vopr. det. dietol. (Pediatric Nutrition). 2019; 17(5): 62–69. (In Russian)