The semiotics of lesions of the gastrointestinal tract in connective tissue dysplasia in children

The article analyses the results of studies dealing with specific lesions of the gastrointestinal tract in children with connective tissue dysplasia (CTD). A sharp change of human living conditions in the 20th–21st centuries has resulted in considerable disturbances of the stability and balance of the physiological systems: the classical course of many diseases has changed, entailing diagnostic pitfalls and therapeutic errors, a higher number of complications, and also a growing percentage of allergic and autoimmune, hereditary pathologies. A higher prevalence of gastrointestinal diseases, including, among others, the paediatric population, necessitates studying specific lesions of the gastrointestinal tract in children who have signs of connective tissue dysplasia. Numerous publications report of a close relationship between CTD and disorders of the gastrointestinal tract, describing such conditions as visceroptosis of abdominal organs, cardiac sphincter incompetence, gastroesophageal and duodenogastral refluxes, inflections, deformities, abnormal position of the gallbladder, dolichosigmoid, megacolon, early onset of chronic gastroduodenitis with diffuse lesion of gastric mucosa and formation of inflammatory-destructive changes, frequent exacerbations of these diseases. The studies explaining multiple changes in the clinical picture of digestive disorders in children make it possible to avoid diagnostic and therapeutic errors.
Key words: visceroptosis, gastroduodenitis, connective tissue dysplasia, gastrointestinal tract, reflux disease, ecological pathology
For citation: Nesterenko Z.V. The semiotics of lesions of the gastrointestinal tract in connective tissue dysplasia in children. Vopr. dietol. (Nutrition). 2020; 10(1): 27–37 (In Russian). DOI: 10.20953/2224-5448-2020-1-27-37


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