The vitamin status in patients of a tuberculosis outpatient clinic

The objective. To assess the vitamin А, Е, D, В2 and carotene status in patients of a tuberculosis outpatient clinical centre.

Patients and methods. We assessed the vitamin status in 46 patients (32 men and 14 women) aged 18–60 years with newly diagnosed clinical forms of pulmonary tuberculosis.

Results. In the overwhelming majority of patients (91.3%) 25(ОН)D concentration in blood serum did not reach the lower normal limit, a marked vitamin D deficiency (<20 ng/ml) was found in 82.6% of individuals. Vitamin В2 deficiency was found in 47.8% of patients. Only 21.7% of the examined patients had optimal levels of this vitamin (serum levels >10 ng/ml). In more than a half of patients, retinol concentrations in blood serum were closer to the lower normal limit, its decreased concentrations were found in 19.6%, which exceeds the commonly found incidence of vitamin А deficiency among the practically healthy population of the Russian Federation. Profound deficiency (<20 μg/dl) was diagnosed in 6.5% of individuals. Insufficient serum carotene levels were found in 3/4 of all examined patients. Lower tocopherol levels were found in 3 men, in 32.6% of patients tocopherol concentrations exceeded the upper normal limit. Only 1 female patient had an adequate micronutrient status; deficiency of 1 vitamin was observed in 19.6% of the examined patients, lower serum levels of 2 vitamins simultaneously – in 26.0%, multi-hypovitaminosis – in 52.2% of individuals.

Conclusion. A high incidence of a combined vitamin deficiency in tuberculosis patients necessitates the use of vitamin complexes that would include vitamins D, А, В2, В6.

Key words: vitamins, vitamin deficiency, blood serum concentration, multivitamin deficiency, tuberculosis.

For citation: Vrzhesinskaya O.A., Kodentsova V.M., Beketova N.A., Kosheleva O.V., Vorozhko I.V., Makhmutov I.F., Alekseev A.P. The vitamin status in patients of a tuberculosis outpatient clinic. Вопросы диетологии. 2016; 6(4): 23–28.
DOI: 10.20953/2224-5448-2016-4-23-28

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