Infectious Diseases

Rotavirus infection in children with somatic disorders: clinical manifestation and disease course

The objective. To analyze features of a demonstration and the course of a rotavirus infection at children with somatic pathology.
Patients and methods. We рresented the course of rotavirus infection in 45 children with somatic pathology (15 children with primary ketoacidosis, 15 children with cerebral palsy, 15 premature infants), were used clinical, biochemical, bacteriological, instrumental methods. Rotavirus infection was confirmed by the release of rotavirus antigen in faeces using ELISA.
Results. Authentically more expressed indicators of acetonuria (р = 0.005; χ2) at the beginning rotavirus infection and dehydration were characteristic at children with primary ketoacidosis, more expressed fever in an onset of the illness and toxicosis were characteristic of children with a cerebral palsy (р < 0.001, χ2), at premature children the rotavirus infection was the cause of long diarrhea and slower increase of weight. Early transfer to artificial feeding, microbiological disturbances of intestines were adverse factors of the anamnesis of life at premature children, pregnancy toxicosis – at children with primary ketoacidosis. The birth trauma and perinatal damage of a brain are more often revealed in the anamnesis at children with a cerebral palsy.
Conclusion. The rotavirus infection at children with somatic pathology changed a clinical picture and promoted earlier demonstration of a basic disease, being the reason of more severe forms of a disease and failures.
Key words: rotavirus infection, children, cerebral palsy, prematurity, primary ketoacidosis
For citation: Gorelov A.V., Denisyuk N.B. Rotavirus infection in children with somatic disorders: clinical manifestation and disease course. Infekc. bolezni
(Infectious diseases). 2019; 17(2): 40–45. (In Russian).

DOI: 10.20953/1729-9225-2019-2-40-45

Яндекс.Метрика